Table 2.

Associations of postdiagnosis waist circumference and mortality among 621 breast cancer survivors in the Health, Eating, Activity, and Lifestyle study

Waist circumference	Multivariate hazard ratios (95 % CI) death from any cause					Multivariate hazard ratios (95 % CI) breast cancer death
	Q1 (59.4–79.5 cm)	Q2 (79.8–88.7 cm)	Q3 (88.8–99.0 cm)	Q4 (99.1–150.0 cm)	p trend	Q1 (59.4–79.5 cm)	Q2 (79.8–88.7 cm)	Q3 (88.8–99.0 cm)	Q4 (99.1–150.0 cm)	p trend
N	156	153	158	154		156	153	158	154
Deaths	23	23	25	36		10	10	10	18
Base modela	1.00	1.41 (0.75, 2.67)	2.01 (0.92, 4.36)	3.06 (1.16, 8.03)	0.023	1.00	1.38 (0.54, 3.53)	1.92 (0.60, 6.17)	3.22 (0.76, 13.6)	0.11
Full modelb	1.00	1.48 (0.78, 2.81)	1.87 (0.86, 4.06)	2.99 (1.14, 7.86)	0.033	1.00	1.39 (0.54, 3.58)	1.66 (0.52, 5.35)	2.69 (0.69, 12.01)	0.145
Full model + C-peptidec	1.00	1.39 (0.71, 2.71)	1.78 (0.77, 4.13)	2.74 (1.00, 7.52)	0.05	1.00	1.35 (0.51, 3.59)	1.96 (0.59, 6.55)	2.89 (0.64, 13.06)	0.167
Full model + HOMAd	1.00	1.28 (0.66, 2.48)	1.62 (0.69, 3.80)	2.19 (0.79, 6.10)	0.133	1.00	1.31 (0.49, 3.48)	1.78 (0.51, 6.14)	2.20 (0.46, 10.49)	0.32
Full model + IGF1-BP3 ratioe	1.00	1.39 (0.72, 2.68)	1.77 (0.77, 4.06)	3.07 (1.13, 8.35)	0.028	1.00	1.49 (0.56, 3.93)	2.11 (0.64, 6.93)	3.39 (0.76, 15.20)	0.111
Full model + C-reactive proteinf	1.00	1.13 (0.58, 2.22)	1.41 (0.61, 3.29)	2.13 (0.78, 5.80)	0.129	1.00	1.22 (0.45, 3.28)	1.52 (0.43, 5.38)	2.33 (0.50, 10.9)	0.276
Full model + adiponecting	1.00	1.28 (0.66, 2.48)	1.58 (0.67, 3.71)	2.45 (0.90, 6.67)	0.077	1.00	1.27 (0.48, 3.39)	1.74 (0.50, 6.00)	2.56 (0.55, 11.92)	0.23

^aAdjusted for measured BMI (<18.5, 18.5–24.9, 25–29.9, 30–34.9, 35+); treatment(surgery, +radiation, +chemo, +radiation and chemo); number of activity-limiting comorbidities; race/ethnicity (non-Hispanic white, Hispanic, African-American, other); Healthy Eating Index 2005 score quartiles

^bBase model + adjustment for postdiagnosis recreational physical activity (0, 0.1–8.9, 9 + MET-h/wk)

^cAmong 562 women

^dAmong 546 women

^eAmong 561 women

^fAmong 556 women

^gAmong 560 women