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FDG PET images with normal and abnormal findings. (a) Axial FDG PET image in a patient without dementia shows a high level of cortical uptake throughout the brain. (b) Axial FDG PET image in a patient with advanced Alzheimer disease shows severe cortical hypometabolism involving both the frontal and parietal lobes. Note the relative sparing of the sensorimotor cortices (arrows), which is a classic finding of Alzheimer disease.
