Table 3.

GRADE assessment of evidence15

Assigned GRADE quality	Description
High	Further research is very unlikely to change confidence in the estimate of effect
Moderate	Further research is likely to have an important impact on confidence in the estimate of effect and may change the estimate
Low	Further research is very likely to have an important impact on confidence in the estimate of effect and is likely to change the estimate
Very low	Any estimate of effect is very uncertain

GRADE, Grading of Recommendations, Assessment, Development and Evaluation.