Table 2.

Nominal significant associations for variants identified for meta‐analysis using the allelic contrast genetic model with credibility factors in (recurrent) acute pancreatitis

									Effect size		Heterogeneity		Credibility
Gene	Variant	Group	Minor allele	Model	Ethnicity	No. of cases	No. of controls	No. of studies	OR	P	I 2 (%)	P	BFDP	Venice	Overall
SPINK1	rs17107315	AP	C	Allelic	Mixed	1493	2595	9	2·87 (1·89, 4·34)	6·3 × 10−7	0·0	0·493	0·055	AAA	A
SPINK1	rs17107315	AP	C	Allelic	White	1085	1687	5	2·49 (1·55, 3·98)	1·5 × 10−4	0·0	0·244	0·529	AAA	A
SPINK1	rs17107315	RAP	C	Allelic	Mixed	233	1300	3	7·51 (3·20, 17·64)	3·7 × 10−6	15	0·389	0·75	AAA	A
SPINK1	rs17107315	RAP	C	Allelic	White	136	758	2	5·65 (2·69, 11·88)	4·9 × 10−6	0·0	0·847	0·664	BAA	B
ALDH2	rs671	AP	A	Allelic	Asian	350	272	2	0·48 (0·36, 0·64)	3·3 × 10−7	0·0	0·415	0·008	BAA	B
IL1B	rs1143634	AP	A	Allelic	Asian	997	899	4	1·23 (1·03, 1·45)	0·018	0·0	0·318	0·788	AAC	C
IL6	rs1800795	AP	C	Allelic	Asian	607	607	2	1·22 (1·00, 1·47)	0·045	0·0	0·726	0·882	AAA	C
GSTT1	Null	AP	Null	Allelic	White	575	804	4	0·66 (0·44, 0·99)	0·045	41·8	0·138	0·907	AAA	C
IL18	rs1946518	AP	T	Allelic	Asian	325	418	2	1·25 (1·00, 1·57)	0·049	0·0	0·781	0·905	BAA	C

Values in parentheses are 95 per cent confidence intervals. OR, odds ratio; BFDP, Bayesian false‐discovery probability; AP, acute pancreatitis; RAP, recurrent acute pancreatitis.