Table 3.

Nominal significant associations for variants identified for meta‐analysis using dominant or recessive genetic models with credibility factors in (recurrent) acute pancreatitis

									Effect size		Heterogeneity		Credibility
Gene	Variant	Group	Minor allele	Model	Ethnicity	No. of cases	No. of controls	No. of studies	OR	P	I 2 (%)	P	BFDP	Venice	Overall
IL1B	rs16944	AP	A	Dominant	Asian	857	861	4	1·23 (1·06, 1·42)	0·005	0·0	0·519	0·622	AAA	A
IL6	rs1800795	AP	C	Recessive	Asian	607	607	2	1·64 (1·15, 2·32)	0·006	0·0	0·685	0·754	AAA	A
IL18	rs187238	AP	G	Dominant	Asian	325	418	2	1·47 (1·18, 1·82)	4·9 × 10−4	0·0	0·328	0·234	BAA	B
CCL2	rs1024611	RAP	G	Dominant	Mixed	302	652	2	2·19 (1·23, 3·89)	0·008	58·6	0·120	0·876	BCA	C
CXCL8 (IL8)	rs4073	AP	T	Recessive	Mixed	1770	1990	9	1·29 (1·06, 1·57)	0·010	57·7	0·015	0·760	ACC	C
CXCL8 (IL8)	rs4073	AP	T	Recessive	White	368	400	4	1·19 (1·01, 1·40)	0·034	0·0	0·300	0·885	BAC	C
IL10	rs1800872	AP	C	Dominant	Mixed	830	802	4	1·17 (1·01, 1·35)	0·040	0·0	0·992	0·880	AAA	C
IL1B	rs1143634	AP	T	Recessive	Mixed	1301	1171	6	1·41 (1·00, 1·99)	0·048	26·9	0·295	0·906	ABC	C

Values in parentheses are 95 per cent confidence intervals. OR, odds ratio; BFDP, Bayesian false‐discovery probability; AP, acute pancreatitis; RAP, recurrent acute pancreatitis.