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. 2019 Dec 3;4(1):3–15. doi: 10.1002/bjs5.50231

Table 4.

Nominal significant associations for variants identified for meta‐analysis with credibility factors comparing patients with mild and severe acute pancreatitis

Effect size Heterogeneity Credibility
Gene Variant Group Minor allele Model Ethnicity No. of cases No. of controls No. of studies OR P I 2 (%) P BFDP Venice Overall
TNF rs1800629 AP A Recessive Mixed 703 702 6 0·54 (0·41, 0·71) 1·3 × 10−5 0 0·707 0·041 AAC C
GSTP1 rs1695 AP G Recessive White 282 125 2 1·43 (1·05, 1·93) 0·022 0 0·950 0·845 BAA C
CXCL8 (IL8) rs4073 AP T Dominant Mixed 387 200 6 0·74 (0·56, 0·98) 0·039 29 0·159 0·950 BBC C

Values in parentheses are 95 per cent confidence intervals. OR, odds ratio; BFDP, Bayesian false‐discovery probability; AP, acute pancreatitis; RAP, recurrent acute pancreatitis.