Table 4.
Effect size | Heterogeneity | Credibility | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Variant | Group | Minor allele | Model | Ethnicity | No. of cases | No. of controls | No. of studies | OR | P | I 2 (%) | P | BFDP | Venice | Overall |
TNF | rs1800629 | AP | A | Recessive | Mixed | 703 | 702 | 6 | 0·54 (0·41, 0·71) | 1·3 × 10−5 | 0 | 0·707 | 0·041 | AAC | C |
GSTP1 | rs1695 | AP | G | Recessive | White | 282 | 125 | 2 | 1·43 (1·05, 1·93) | 0·022 | 0 | 0·950 | 0·845 | BAA | C |
CXCL8 (IL8) | rs4073 | AP | T | Dominant | Mixed | 387 | 200 | 6 | 0·74 (0·56, 0·98) | 0·039 | 29 | 0·159 | 0·950 | BBC | C |
Values in parentheses are 95 per cent confidence intervals. OR, odds ratio; BFDP, Bayesian false‐discovery probability; AP, acute pancreatitis; RAP, recurrent acute pancreatitis.