Table 3.
Studies of Intereye Difference for MSON
|
Authors |
MSON (Patient) |
Control (Subject) |
OCT Device |
Retina Layer |
Intereye Difference Cutoff |
Sensitivity, % |
Specificity, % |
| Hu et al. (present study) | 30 | 63 | UHR-OCT | U Zone | 6 μm (optimized) | 69 | 97 |
| 4 μm | 73 | 86 | |||||
| 3 μm | 77 | 81 | |||||
| Nolan et al.14 | 45 | 31 | SD-OCT | pRNFL Ave | 5 μm | 76 | 75 |
| 6 μm | 62 | 81 | |||||
| Coric et al.11 | 62 | 63 | SD-OCT | GCIPL percentage | 20% | 34 | 100 |
| 6% | 70 | 97 | |||||
| Xu et al.12 | 51* | 233 | HD-OCT | pRNFL Ave | 9 μm | 73 | |
| GCIPL Ave | 6 μm | 96 | |||||
| Nolan et al.13 | 477 | 368 | SD-OCT | pRNFL Ave | 5 μm | 71 | 65 |
| GCIPL Ave | 4 μm | 68 | 77 |
*
Including patients with various disorders such as MS (51%), idiopathic (41%), and neuromyelitis optica spectrum disorder (8%).