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. 2020 Jan 21;2020:2354108. doi: 10.1155/2020/2354108

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Copyright © 2020 Yunting Zhou et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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VAD causes reduced diversity/richness and alters cluster and composition of intestinal microbiota. (a) Alpha-diversity assay of intestinal microbiota of mice from VAS, VAD, and VADR groups. (b) Beta-diversity of intestinal microbiota of mice described for (a): unweighted UniFrac PCoA plotted against PC1 versus PC2 axes. (c) Cluster analysis for bacterial communities of mice described in (a). (c) Heat map of key OTUs of mice described for (a). (d, e) Bacterial composition at the phylum level of mice described for (a). (f) Akkermansia muciniphila composition at the phylum level of mice described for (a). Error bars represent S.E (n = 6/group). ^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001.