(b).
| Characteristics | Model 4 | P value | Model 5 | P value | Model 6 | P value |
|---|---|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | ||||
| ET B | 4.668 (1.298–16.786) | 0.018∗ | 3.096 (1.096–8.742) | 0.033∗ | 5.786 (0.935–35.801) | 0.059 |
| Male | 1.871 (0.560–6.254) | 0.309 | 1.218 (0.434–3.416) | 0.708 | 2.141 (0.371–12.347) | 0.394 |
| Age (years) | 1.059 (1.006–1.114) | 0.029∗ | 1.065 (1.021–1.110) | 0.003∗ | 1.070 (1.001–1.144) | 0.047∗ |
| BMI (kg/m2) | 0.918 (0.810–1.041) | 0.183 | 0.929 (0.828–1.043) | 0.047∗ | — | — |
| TG (mmol/l) | 1.760 (1.030–3.006) | 0.038∗ | 1.612 (1.032–2.518) | 0.036∗ | 0.915 (0.658–1.273) | 0.915 |
| HDL-C (mmol/l) | 0.014 (0.002–0.107) | <0.001∗ | 0.037 (0.007–0.191) | <0.001∗ | 0.170 (0.016–1.808) | 0.170 |
| HOMA-β | 0.956 (0.938–0.974) | <0.001∗ | — | — | — | — |
| HOMA-IR | — | — | 0.903 (0.386–2.112) | 0.814 | — | — |
| Gutt-ISI | — | — | — | — | 0.000 (0.000–0.000) | <0.001∗ |
Model 1 had no adjusted variable. Model 2 is adjusted for age, gender, and BMI. Model 3 is adjusted for model 2 plus TG and HDL-C. Model 4 is adjusted for model 3 plus HOMA-β. Model 5 is adjusted for model 3 plus HOMA-IR. Model 6 is adjusted for model 3 plus Gutt-ISI, since body weight was used to calculate Gutt-ISI, BMI was removed in Model 6. ∗P < 0.05. ET B: enterotype Bacteroides; BMI: body mass index; TGs: triglyceride levels; HDL-C: high-density lipoprotein cholesterol; HOMA-β: homeostasis model assessment of β-cell function; HOMA-IR: homeostasis model assessment of insulin resistance; Gutt-ISI: Gutt-insulin sensitivity index.