Table 1.
Values of EC 50 and Emax in the control and test groups: resveratrol + 8Br-cGMP 0.01 M/l and 8Br-cGMP 0.1 M/l.
| n 1 | EC50 (M/l) | E max (%)2 | p | |
|---|---|---|---|---|
| Control (Res−) | 8 | 4.53 ± 1.2 × 10−8 | 100.0 | — |
| 8Br-cGMP 0.01 M/l (Res−) | 10 | 2.77 ± 0.56 × 10−7∗p < 0.0001 | 99.0 ± 3.0 | nsa |
| 8Br-cGMP 0.01 M/l + resveratrol | 14 | 3.43 ± 0.43 × 10−7 | 76.4 ± 3.7 | p < 0.0001b |
| 8Br-cGMP 0.1 M/l + resveratrol | 12 | 3.43 ± 0.43 × 10−7 | 61.6 ± 4.0 | p < 0.0001c |
1The number of CRC used for the calculation; 2Emax calculated as a % of the maximum tissue response to PHE; ap value calculated relative to the control (Res−); bp value calculated relative to 8Br-cGMP 0.01 M/l (Res−); cp value calculated relative to 8Br-cGMP 0.01 M/l (Res+). All data are means ± SD.