Fig 2. Baseline and post-operative pain intensity measured using visual analogue scale according to the assessment time and endodontic protocol.

Circles indicate the means and bars represent the standard error. P-values calculated using the Mann-Whitney test. HFLC–Hand-file and lateral compaction; SFSC–Single-file and single-cone; VAS–Visual analogue scale. Peak = most intense pain felt by the patient in the first 24 hours after the treatment.