Figure 1:

Box-whisker plot shows summary of the effect of tumorigenesis induced by radiofrequency ablation (RFA) in metastatic colorectal mouse tumor models. Comparisons of tumor load and number of Ki-67– and CD34-positive cells between RFA and sham procedures are shown. Tumor number and tumor area ratio in the mice livers that underwent RFA were significantly greater than those in mice that underwent a sham procedure. Likewise, the tumors identified in the RFA group had greater proliferative indexes and increased neovascularization than their littermates in the sham group. P < .05 for all comparisons of RFA versus sham procedure. IHC = immunohistochemistry.