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. 2020 Feb 3;15(2):e0227823. doi: 10.1371/journal.pone.0227823

Table 3. Relationships between S. epidermidis colonization (counts expressed as log10 CFU/g) and the main clinical and demographic data.

Parameter Positive samples and counts P value
n (%) Microbial Counts Median (IQR)
Gestational age < 28 weeks 16 (62%) 7.91 (6.47–8.35) 0.958
> 28 weeks 10 (38%) 7.51 (6.61–8.56)
Birth weight < 1000 g 11 (42%) 7.98 (7.03–8.37) 0.391
> 1000 g 15 (58%) 7.46 (6.18–8.48)
Delivery mode Vaginal 12 (46%) 7.47 (6.67–7.94) 0.291
Cesarean section 14 (54%) 8.31 (6.20–8.71)
Antibiotherapy (days) No Ab or <3 days 10 (38%) 7.46 (6.61–8.12) 0.399
>3 days 16 (62%) 7.95 (6.47–8.66)
Mechanical ventilation YES 16 (62%) 7.95 (7.20–8.50) 0.246
NO 10 (38%) 7.08 (5.98–8.13)
CPAP < 7 days 13 (50%) 7.36 (5.78–8.32) 0.238
> 7 days 13 (50%) 7.98 (7.45–8.42)
Parenteral nutrition < 7 days 15 (58%) 7.57 (6.64–8.68) 0.736
> 7 days 11 (42%) 7.92 (6.24–8.31)
Enteral feeding tubes < 45 days 11 (42%) 7.46 (6.70–8.48) 0.835
> 45 days 15 (58%) 7.92 (5.74–8.37)
CVN < 7 days 13 (50%) 7.57 (6.70–8.64) 0.700
> 7 days 13 (50%) 7.90 (5.78–8.32)
NICU stay < 45 days 15 (58%) 7.45 (6.18–8.11) 0.119
> 45 days 11 (42%) 8.30 (7.64–8.57)
Hospital stay < 60 days 13 (50%) 7.46 (6.70–8.64) 0.959
> 60 days 13 (50%) 7.92 (5.78–8.32)
Predominance of MOM feedings No 5 (19%) 7.90 (7.57–8.30) 0.625
Yes 21 (81%) 7.46 (5.78–8.42)
S. epidermidis Sepsis No 21 (81%) 7.90 (6.70–8.64) 0.228
Yes 5 (19%) 6.70 (5.78–7.92)
Sampling time Meconium (n = 16) 6 (38%) 6.80 (4.80–8.80) 0,098*
1st week feces (n = 18) 16 (89%) 7.85 (7.00–8.38)
2nd week feces (n = 23) 13 (57%) 6.70 (6.30–7.30)
3rd week feces (n = 24) 12 (50%) 6.50 (5.93–7.53)
4th week feces (n = 11) 3 (27%) 7.70 (7.65–8.50)

*Friedman test.