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. 2019 Feb 21;19(2):e12907. doi: 10.1111/acel.12907

Figure 3.

Figure 3

Scatterplot displaying relationship between age‐related rate of change in DNA methylation and mortality. The empty dots are CpGs significantly methylated with age (FDR <0.05, the larger the dots the higher the statistical significance). The red dots are CpGs associated with mortality with p < 0.05 in the Cox regression model. The figure shows that age‐associated CpGs predominantly contribute to reduced risk of death