Table 2.
Molecular mutations in primary pulmonary lymphoepithelioma‐like carcinoma (PLELC) at the Guangdong Lung Cancer Institute (GLCI)
| Patients | Mutation status | Detection method | TNM stage | EBERs |
|---|---|---|---|---|
| 1 | EGFR 21 L858R | Sanger sequencing | III | 3+ |
| 2 | EGFR 21 L858R | Sanger sequencing | IV | 3+ |
| 3 | EGFR 20 insertion | ARMS‐PCR | IV | 2+ |
| 4 | EGFR 20 insertion | ARMS‐PCR | II | 3+ |
| 5 | EGFR exon 19/21 | ARMS‐PCR | III | 1+ |
| 6 | ALK fusion | Ventana IHC | IV | 3+ |
| 7 | ALK fusion | Ventana IHC | IV | 3+ |
| 8 | ALK fusion | Ventana IHC | II | 3+ |
ARMS, amplification refractory mutation system; EBERs, Epstein‐Barr virus‐encoding small RNA.