Table 2. Baseline data regarding all episodes of disease progression.
| Characteristic | Total number (% of cohort) |
|---|---|
| Total number of progression episodes | 40 |
| Patterns of progression | |
| Local only | 23 (57.5) |
| Distant only | 9 (22.5) |
| Local + distant | 8 (20) |
| Distant metastases | 17 episodes total |
| Spinal column metastases | 7 (17.5) |
| Leptomeningeal disease | 7 (17.5) |
| Systemic metastases | 13 (32.5) |
| Patterns of local progression | 38 episodes total |
| Infield failure | 18 (47.4) |
| Marginal failure | 5 (13.2) |
| Outfield failure | 15 (39.4) |
| Treatment paradigms | |
| Local progression | 38 episodes |
| Repeat surgery | 9 (24) |
| Chemotherapy | 12 (32) |
| Stereotactic radiosurgery | 13 (34) |
| Systemic metastases | 17 episodes total |
| Surgery | 7 (41) |
| Chemotherapy | 13 (76) |
| Radiation therapy | 8 (47) |