Table 1.

Summary of the Australian Melanoma Family Study (development dataset) and Leeds Melanoma Case-Control Study (external validation dataset)

Study	Study design	Geographical location	Cases/ Controls	Case ascertainment	Control ascertainment	Diagnosis age	Diagnosis years	Data collection
Australian Melanoma Family Study	Population-based case-control-family study	Brisbane, Sydney and Melbourne, Australia	461/329	State cancer registries	Electoral rolla and spouses or friends of cases	18–39 years	2000–2002	Skin examinations by dermatology trainees, and self-administered and telephone-administered questionnaires
Leeds Melanoma Case-Control Study	Population-based case-control study	Yorkshire, United Kingdom	960/513	Clinicians, pathology registers and cancer registries	General practiceb	18–76 years	2000–2005	Skin examinations by research nurses, and self-administered and telephone-administered questionnaires

^aPopulation-based controls were identified from the electoral roll and frequency-matched to cases by geographical location, age and sex; and spouse/friend controls were nominated by the cases.

^bControls were identified from the cases’ general practice patient lists and were frequency-matched to cases by age and sex