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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Schizophr Res. 2019 Aug 4;217:124–135. doi: 10.1016/j.schres.2019.07.036

Figure 1.

Figure 1.

Volcano plot showing the log2 fold-change in gene expression between bipolar disorder (BD) cases and unaffected comparison subjects (horizontal axis) relative to p-value for the fold-change estimate (vertical axis). An orange horizontal dotted line denotes p = 0.05. A red dotted horizontal line denotes a Bonferroni significance threshold (adjusted p = 0.05/17201 = 2.91e–06). Genes shaded red showed an association with BD at a Bonferroni adjusted p < 0.05. Genes shaded in orange showed an association with BD at a Benjamini-Hochberg false discovery rate (FDR) p < 0.05. Genes shaded blue showed an absolute log2 fold-change > 0.25 in BD cases.