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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Schizophr Res. 2019 Aug 4;217:124–135. doi: 10.1016/j.schres.2019.07.036

Figure 3.

Figure 3.

(A) Four WGCNA modules (ME15, ME17, ME22, and ME23) identified from transcriptome-wide peripheral blood gene expression data were found to be differentially expressed in bipolar disorder (BD) cases relative to unaffected comparison subjects. (B) The top five most significantly over-represented Gene Ontology (GO) gene sets found in the four BD-associated WGCNA modules. (C) A heat map showing the degree of similarity between pairs of modules based on the similarity of the sets of GO gene sets that were over-represented in the four BD-associated modules. Similarity index is on a 0 – 1 scale, with a value closer to 1.0 indicating high similarity.