Figure 3.

Morphological and metastatic characteristics of parental and gemcitabine (GEM)‐resistant cell lines. A, Morphological characteristics of parental and GEM‐resistant cells were determined using an inverted microscope. Red arrows indicate cellular pseudopods. B and C, Transwell assays showed increased migratory and invasive abilities among BxPC‐3‐GR cells compared with BxPC‐3 cells. D and E, Comparisons of migration and invasion between CFPAC‐1 and CFPAC‐1‐GR cells using transwell assays detected no significant differences. ***P < .001; comparisons indicated by lines. NS, no significant difference. Scale bar, 100 µm