Table 2.
Drug | CFPAC‐1 | CFPAC‐1‐GR | |
---|---|---|---|
IC50 (nmol/L)a | IC50 (nmol/L) | RIb | |
Gemcitabine | 3 ± 0.2 | 631 ± 59 | 210.3 |
Capecitabine | 548 ± 20 | 30 553 ± 830 | 55.8 |
5‐Flourouracil | 34 ± 3 | 599 ± 150 | 17.6 |
Oxaliplatin | 4455 ± 745 | 16 137 ± 3478 | 3.6 |
Irinotecan | 1540 ± 792 | 3437 ± 655 | 2.2 |
Docetaxel | 30 ± 5 | 26 ± 9 | 0.9 |
Cisplatin | 3463 ± 228 | 1902 ± 162 | 0.5 |
The IC50 values were defined as the concentration of cells inhibiting growth at 50%.
Drug resistance index (RI) was determined by dividing IC50 values of CFPAC‐1 and CFPAC‐1‐GR.