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. 2019 Dec 19;9(3):1230–1241. doi: 10.1002/cam4.2676

Table 2.

Expression levels of the identified 7 miRNAs in the three independent stages (presented as mean ± SD; ΔCT, relative to cel‐miR‐39)

miRNA Training stage Testing stage External validation stage
NPC NC FC P‐value NPC NC FC P‐value NPC NC FC P‐value
let‐7b‐5p 3.17 ± 0.69 4.30 ± 0.82 2.19 <.001 2.86 ± 1.51 4.70 ± 1.37 3.59 <.001 3.70 ± 0.93 5.16 ± 0.70 2.76 <.001
miR‐140‐3p 6.00 ± 1.16 6.63 ± 1.46 1.54 .034 4.72 ± 2.14 6.54 ± 1.81 3.54 <.001 7.58 ± 0.72 8.35 ± 0.80 1.71 <.001
miR‐144‐3p 6.04 ± 1.27 6.67 ± 1.15 1.55 .020 3.81 ± 1.72 5.15 ± 2.11 2.53 <.001 5.53 ± 1.67 6.31 ± 1.67 1.72 .001
miR‐17‐5p 2.28 ± 0.79 4.10 ± 0.99 3.54 <.001 0.98 ± 1.76 3.55 ± 1.15 5.92 <.001 4.34 ± 1.05 5.76 ± 1.03 2.66 <.001
miR‐20b‐5p 5.55 ± 0.75 7.05 ± 0.93 2.84 <.001 4.31 ± 1.85 6.65 ± 1.33 5.06 <.001 6.51 ± 0.95 7.88 ± 0.88 2.57 <.001
miR‐205‐5p 9.27 ± 1.26 10.09 ± 1.09 1.77 .014 7.94 ± 1.96 9.28 ± 2.00 2.53 <.001 9.02 ± 2.00 9.87 ± 1.40 1.80 .047
miR‐20a‐5p 4.34 ± 1.08 6.38 ± 1.09 4.12 <.001 5.86 ± 2.60 7.70 ± 1.87 3.56 <.001 5.14 ± 0.66 5.93 ± 0.61 1.74 .028

Abbreviations: FC, fold change; NCs, normal controls; NPC, nasopharyngeal carcinoma.