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. 2019 Dec 11;111(2):360–368. doi: 10.1093/ajcn/nqz296

FIGURE 2.

FIGURE 2

Predicted indicators of offspring's childhood obesity, according to gestational weight gain (per 1 kg) by the MTNR1B rs10830962 genotype. The slope represents the β coefficient. The β coefficients were: 0.009 (SE 0.018), 0.026 (SE 0.010), and 0.061 (SE 0.010) for childhood BMI-for-age z-score; 0.004 (SE 0.016), 0.021 (SE 0.009), and 0.063 (SE 0.009) for weight-for-age z-score; 0.017 (0.077), 0.106 (0.044), and 0.263 (0.047) for waist circumference (cm); and 0.064 (SE 0.117), 0.134 (SE 0.060), and 0.373 (SE 0.059) for body fat percentage, respectively (P-interaction = 0.012, 0.001, 0.003, and 0.012, respectively). Maternal gestational weight gain was significantly associated with greater childhood BMI-for-age z-scores,weight-for-age z-score, body fat, and waist circumference in women carrying the GG genotype (all P < 0.0001).C, cytosine; G, guanine; SE, standard error.