Table 3.
Pathologic characteristics
| Characteristic | Interval ≤ 7 wks (n = 60) | Interval > 7 wks (n = 97) | P value |
|---|---|---|---|
| ypT stage | .949a | ||
| T0 | 16 (26.7) | 29 (29.9) | |
| T1 | 3 (5.0) | 3 (3.1) | |
| T2 | 15 (25.0) | 21 (21.6) | |
| T3 | 22 (36.7) | 37 (38.1) | |
| T4 | 4 (6.6) | 7 (7.2) | |
| ypN stage | .340a | ||
| N0 | 49 (81.7) | 84 (86.6) | |
| N1 | 5 (8.3) | 9 (9.3) | |
| N2 | 6 (10.0) | 4 (4.1) | |
| pCR (ypT0N0) | 15 (25.0) | 26 (26.8) | .803b |
| T downstaging (ypT < cT) | 38 (63.3) | 65 (67.0) | .637b |
| N downstaging (ypN < cN) | 38 (63.3) | 67 (69.1) | .458b |
| Tumor regression grade | .561a | ||
| 0 | 15 (25.0) | 29 (29.9) | |
| 1 | 20 (33.3) | 35 (36.1) | |
| 2 | 24 (40.0) | 29 (29.9) | |
| 3 | 1 (1.7) | 4 (4.1) | |
| Tumor size, cm | 4.3 (0‐9.0) | 4.0 (0‐8.7) | .425c |
| Number of harvested lymph nodes | 9 (0‐24) | 8 (0‐25) | .589c |
| Number of positive lymph nodes | 0 (0‐15) | 0 (0‐17) | .746c |
| CRM involved | 2 (3.3) | 2 (2.1) | .495a |
| Lymphovascular invasion | 5 (8.3) | 2 (2.1) | .108a |
| Perineural invasion | 1 (1.7) | 4 (4.1) | .650a |
Data are median (range) or n (%).
pCR, pathologic complete remission; CRM, circumferential resection margin.
a
Data were calculated using the Fisher exact test.
b
Data were calculated using the χ2 test.
c
Data were calculated using the Mann‐Whitney U test