Table 1.
Recruited patients with advanced CKD incl. dialysis-dependency and control volunteers.
| Parameters | All Patients | Renal impairment | Control | p value |
|---|---|---|---|---|
| n = 23 (100%) | n = 11 (48%) | n = 12 (52%) | ||
| Clinical characteristics | ||||
| Age | 68.5 ± 3.4 | 72.4 ± 2.8 | 0.38 | |
| Creatinine | 4.2 ± 0.85 | 1.1 ± 0.08 | 0.0011 | |
| GFR | 19.2 ± 3.1 | 65.1 ± 5.7 | 0.0001 | |
| CRP | 1.3 ± 0.4 | 2.0 ± 0.7 | 0.4098 | |
| Hb | 11.6 ± 0.5 | 11.9 ± 0.6 | 0.7057 | |
| WBC | 8517 ± 726 | 7779 ± 409 | 0.3756 | |
| platelets | 197.9 ± 17.8 | 214.8 ± 18.1 | 0.5156 | |
| female | 3 (27%) | 3 (25%) | 1 | |
| Dialysis | 4 (36%) | 0 (0%) | 0.0373 | |
| Diabetes | 6 (55%) | 5 (42%) | 0.6843 | |
| Hypertension | 10 (91%) | 10 (83%) | 1 | |
| Medication | ||||
| Betablockers | 8 (73%) | 10 (83%) | 0.6404 | |
| Statin | 9 (82%) | 10 (83%) | 1 | |
| ACE-Inh. | 4 (36%) | 4 (33%) | 1 | |
| AT-1 Inh. | 2 (18%) | 3 (25%) | 1 | |
| ASA | 6 (55%) | 7 (58%) | 1 | |
| Clopidogrel | 3 (27%) | 2 (17%) | 0.6404 | |
| Ticagrelor | 2 (18%) | 5 (42%) | 0.3707 | |
| Phenprocoumon | 0 (0%) | 1 (8%) | 1 | |
| DOAK | 1 (9%) | 1 (8%) | 1 | |