Table 3.
Pregnancy Outcomes of Frozen-Thawed Embryos Originating from the Two Regimens
| DYG + hMG | MPA + hMG | P-value | |
|---|---|---|---|
| No. of patients | 95 | 261 | |
| No. of FET cycles | 154 | 367 | |
| No. of embryos transferred per cycle, n (%) | 0.104 | ||
| Single | 33 (21.4) | 57 (15.5) | |
| Double | 121 (78.6) | 310 (84.5) | |
| Embryo stage at transfer, n (%) | 0.213 | ||
| Cleavage stage | 138 (89.6) | 314 (85.6) | |
| Blastocyst stage | 16 (10.4) | 53 (14.4) | |
| Endometrial preparation, n (%) | 0.283 | ||
| Mild stimulation | 78 (50.6) | 167 (45.5) | |
| Hormone replacement therapy | 76 (49.4) | 200 (54.5) | |
| Endometrial thickness (mm) | 9.96±1.60 | 10.01±2.08 | 0.656 |
| Pregnancy outcomes per cycle, n/N (%) | |||
| Biochemical pregnancy rate | 90/154 (58.4) | 238/367 (64.9) | 0.167 |
| Clinical pregnancy rate | 81/154 (52.6) | 219/367 (59.7) | 0.136 |
| Implantation rate | 107/275 (38.9) | 305/677 (45.1) | 0.083 |
| Multiple pregnancy rate | 22/81 (27.2) | 81/219 (37.0) | 0.112 |
| Ectopic pregnancy rate | 2/81 (2.5) | 7/219 (3.2) | 1.000 |
| Miscarriage rate | 12/81 (14.8) | 37/219 (16.9) | 0.665 |
| Live birth rate | 67/154 (43.5) | 175/367 (47.7) | 0.383 |
Note: Data are presented as mean ± standard deviation or number (percentage).
Abbreviations: hMG, human menopausal gonadotropin; DYG, dydrogesterone; MPA, medroxyprogesterone acetate; FET, frozen-thawed embryo transfer.