Table 3.

Uni and multivariate linear regression model for serum and salivary ET-1 levels in all enrolled subjects. Age was included as continuous variable. For periodontitis and CHD, controls served as reference. For gender, male served as reference. For education, primary school served as a reference.

Serum ET-1 levels	Univariate			Multivariate
Variable	B	95% CI	P	B	95% CI	P
CHD	0.377	0.216; 0.447	<0.001	0.064	−0.299; 0.475	0.684
Periodontitis	0.222	0.011; 0.397	0.029	0.123	−0.049; 0.413	0.177
hs-CRP	0.139	0.059; 0.112	<0.001	0.211	0.087; 0.117	<0.001
Age (years)	−0.011	−0.341; 0.012	0.087	−0.045	−0.125; 0.236	0.411
Female gender	0.133	−0.055; 0.412	0.185	0.147	−0.97; 0.412	0.057
Education SES	−0.079	−0.187; 0.064	0.312	−0.078	−0.312; 0.478	0.254
Salivary ET-1 levels
CHD	0.211	0.136; 0.654	<0.001	−0.058	−0.541; 0.313	0.549
Periodontitis	0.055	−0.087; 0.331	0.378	0.008	−0.184; 0.168	0.784
hs-CRP	0.074	0.038; 0.223	<0.001	0.074	0.038; 0.145	<0.001
Age (years)	−0.041	−0.031; 0.009	0.201	0.005	−0.045; 0.036	0.841
Female gender	0.055	−0.145; 0.236	0.491	0.079	−0.044; 0.315	0.231
Total Cholesterol	−0.079	−0.174; −0.012	0.042	−0.87	−0.058; 0.239	0.043
Serum ET-1	0.139	−0.035; 0.413	0.077	−0.028	−0.312; 0.174	0.553