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. 2020 Jan 28;10:3059. doi: 10.3389/fimmu.2019.03059

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Copyright © 2020 Fonseca, Davoli-Ferreira, Santa-Cecília, Guimarães, Oliveira, Kusuda, Ferreira, Alves-Filho, Cunha and Cunha.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activation of immune/glial cells and cytokine expression in the DRGs and spinal cord after peripheral nerve injury in the absence of IL-27. Real-time PCR analysis of the expression of glial markers and pro-inflammatory cytokines relative to Gapdh at days 7, 10, and 14 after SNI or Sham surgery in WT and IL-27^−/− mice: (A) Aif1, (B) Gfap, (C) Tnf, and (D) Il1b expressions in DRGs, (E) Aif1, (F) Gfap, (G) Tnf, and (H) Il1b expressions in spinal cord (n = 7). Data are presented as means ± S.E.M. Data were analyzed by one-way ANOVA followed by Bonferroni post-test.