Figure 2.

Distribution of [11C] Ro15-4513 GABA receptor ligand. After the placebo, the ligand was mainly bound in the medial-inferior prefrontal cingulate cortex, and right and left insula. After dopamine challenge ligand binding is reduced, with a general reduction of between 5% and 20% throughout the cortex. In hippocampal regions there were small foci of increased binding potential. Adapted with permission from Lou et al. (2016).