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. 2020 Feb 3;10:1662. doi: 10.1038/s41598-020-58480-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Average ADC maps for patients with deep (A), superficial (B) and territorial stroke (C). The whole sample is shown in (D). Dark lines contour the IBZ estimate (from the chronic patient sample). Warmer colors indicate more important ADC reductions (units are 10⁻⁶ mm²/s). For display purposes, regions with normal ADC values are not displayed (>0.0015 mm²/s). Stronger ADC decreases are within the IBZ, especially for patients with territorial stroke (C).