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. 2020 Jan 28;7:14. doi: 10.3389/fvets.2020.00014

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Copyright © 2020 Oh, Jun, Kim, Giri, Yun, Kim, Kim, Kang, Han, Kwon and Park.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Signs of necrotizing areas in liver with cytoplasmic vacuolation accompanied by phagocytized bacterial rods, heterophils, and melanomacrophages (arrow) surrounding the area (Scale bar indicating 10 μm). (B) Sever congestion observed in liver of infected fish (Scale bar indicating 50 μm). (C) Signs of vasculitis with cellular debris (arrow) accompanied by diverse immunocyte infiltration surrounding the vessel and macrophage phagocytized bacterial rods (arrowhead) detected in the area (Scale bar indicating 10 μm). (D) Melanomacrophage and heterophils (arrow) concentrated around a bile duct on the liver (Scale bar indicating 10 μm).