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. 2020 Feb 3;10:1721. doi: 10.1038/s41598-020-58331-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Transcription factors frequently associated with motifs. Heatmap reporting transcription factors whose binding sites are associated with motifs in at least 4 different tissues. Columns report each motif/cancer pair while rows report enriched TFs. Motifs are clustered based on the number of shared enriched TFs. The upper bar indicates hypo-methylated motifs in green, hyper-methylated motifs in red, with undefined methylation status in grey.