Table 4.
Main effects of time in structural MRI ROI analysis.
| Brain structure | BA | Hemisphere | Cluster size (# of voxels) | Peak Z | MNI coordinates | p (FWE-corr) | ||
|---|---|---|---|---|---|---|---|---|
| X | Y | Z | ||||||
| Frontal cortex | ||||||||
| Medial OFC | 11 | Right | 3,440 | 6.596 | 8 | 54 | −23 | <0.001* |
| Ventrolateral PFC | 46 | Right | 5,867 | 5.485 | 53 | 44 | 0 | <0.001* |
| Ventrolateral PFC | 10 | Left | 534 | 5.069 | −33 | 49 | −4 | 0.002* |
| Ventromedial PFC | – | Left | 436 | 4.948 | −14 | 54 | −7 | 0.003* |
| Ventromedial PFC | 10 | Right | 140 | 4.658 | 13 | 48 | 3 | 0.011* |
| Hippocampus | – | Left | 332 | 4.340 | −26 | −6 | −20 | 0.002* |
Brain regions that show a significant change in volume comparing pre vs. post-measurements in both groups (training, control). No signficant time × group interaction effect. Two-way repeated measures ANOVA was used. n = 26.
*
p < 0.05 (FWE-corr), bold values indicate significance. BA, Brodmann Area; FWE-corr, family-wise error-corrected; OFC, orbitofrontal cortex; PFC, prefrontal cortex.