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. 2020 Jan 7;34:27–42. doi: 10.1016/j.molmet.2019.12.014

Table 1.

Number of total and 2018 PubMed citations related to insulin resistance and some of the various major cellular pathways that have been implicated in the induction of insulin resistance in obesity. The terms “insulin resistance” or “insulin resistance and” and each of the terms listed in the table under “Cellular pathway” was searched on August 21, 2019. The number of total citations are provided for each of these searches.

Cellular Pathway Total PubMed Citations 2018 PubMed Citations
Insulin Resistance 119,837 8376
Insulin Resistance and …
Protein kinase 11,449 744
Fatty Acids 10,970 668
Cytokines 9331 613
Reactive Oxygen Species 2207 199
Microbiota 1117 228
Hypoxia 852 83
Branched chain amino acids 773 81
miRNA 752 149
Ceramide 713 66
Diacylglycerol 525 32
cAMP 522 21
ER Stress Response 302 29