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. 2020 Jan 28;8:30. doi: 10.3389/fchem.2020.00030

Figure 1.

Figure 1

(A) Some of the structural diversity encountered when the nitro-Mannich reaction was utilized in the synthesis of biologically active substances or their intermediates; (B) the base-catalyzed nitro-Mannich reaction; (C) early catalysts utilized in stereoselective nitro-Mannich reactions.