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PEA treatment reduced lipid accumulation in SD-induced mice LGs. Oil red O staining results indicated that PEA reduced lipid deposition in SD-induced mice LG (A), scale bars: 50 μm. Ultrastructural analysis under transmission electron microscopy revealed that PEA decreased lipid droplets accumulation close to the LG acinar cell nucleus (B). Lipid droplets (red arrows), secretory granules (green arrows).
