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Effects of PEA on PPAR-α− / − mice. The PEA levels in LGs of PPAR-α− / − mice decreased markedly comparing with WT mice (A). PEA could not increase the tear production (B), reduce the LG (C) and acinar cell size (D), and ameliorate lipid deposition (E) in PPAR-α− / − mice. *, P < 0.05, **, P < 0.01 vs. control group, one-way ANOVA followed by Dunette’s post hoc, n = 5.
