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. 2020 Jan 28;10:1646. doi: 10.3389/fphar.2019.01646

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Copyright © 2020 Bai, Sun, Pan, Yang, Li, Wu, Qin, Cao, Zou and Wu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The structure and purity of TMEA. (A) Determination of TMEA by HPLC chromatography; (B) The molecular formula and determination of TMEA by MS chromatography; (C) Determination of TMEA by ¹³C-NMR chromatography; (D) Determination of TMEA by ¹H-NMR chromatography; (E) The best scored docking pose of TMEA in the binding pocket of VEGFR2; (F) The interactions between TMEA and VEGFR2. TMEA, 3,3',4'-trimethylellagic acid; VEGFR2, vascular endothelial growth factor receptor 2.