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. 2020 Jan 28;10:1646. doi: 10.3389/fphar.2019.01646

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Copyright © 2020 Bai, Sun, Pan, Yang, Li, Wu, Qin, Cao, Zou and Wu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TMEA inhibits the tumor growth of SW620 xenograft bearing in nude mice. (A) Tumor volume and (B) Tumor weight of the SW620 xenografts bearing in nude mice after treatment of vehicle solution (control), 5-FU (25 mg/kg, i.p. twice a week for 3 weeks) or TMEA (50, 100, and 100 mg/kg, p.o., daily for 3 weeks). There were eight mice for each group and the data are expressed as mean ± SD. *p < 0.05, **p < 0.01, compared with the control by one-way univariate analysis of variance (ANOVA). TMEA, 3,3',4'-trimethylellagic acid.