Table 2.
Gene ontology (GO) analysis of 35 target genes of miRNA-93 (list by PValue).
| Type | Term | Count | PValue | Genes |
|---|---|---|---|---|
| Molecular Function | protein binding | 26 | 0.000942 | E2F1, KIF23, E2F2, ADARB1, NACC2, HMGB3, EGR2, LDLR, GINS4, SOX4, ELAVL2, DPYSL2, EPHA7, DUSP2, CRY2, SLC2A4, CFL2, RRM2, CYBRD1, FAM129A, POLQ, KATNAL1, SIK1, CIT, FYCO1, KPNA2 |
| Biological Process | lens fiber cell apoptotic process | 2 | 0.007364701 | E2F1, E2F2 |
| Biological Process | plus-end-directed vesicle transport along microtubule | 2 | 0.012853753 | KIF23, FYCO1 |
| Biological Process | glucose homeostasis | 3 | 0.014869797 | CRY2, SLC2A4, SOX4 |
| Molecular Function | MAP kinase tyrosine/serine/threonine phosphatase activity | 2 | 0.023620021 | DUSP2, DUSP8 |
| Cellular Component | nucleus | 17 | 0.024386573 | E2F1, KIF23, NACC2, ADARB1, HMGB3, EGR2, KLF9, GINS4, SOX4, SALL3, DUSP2, CRY2, RRM2, SIK1, KATNAL1, DUSP8, KPNA2 |
| Cellular Component | nucleoplasm | 11 | 0.026806886 | KIF23, E2F1, E2F2, ADARB1, KLF9, RRM2, GINS4, SOX4, ELAVL2, POLQ, KPNA2 |
| Molecular Function | transcription factor activity, sequence-specific DNA binding | 6 | 0.029303045 | SALL3, E2F1, E2F2, EGR2, KLF9, SOX4 |
| Biological Process | entrainment of circadian clock by photoperiod | 2 | 0.036302096 | CRY2, SIK1 |
| Biological Process | cellular response to fatty acid | 2 | 0.041636205 | E2F1, LDLR |
| Biological Process | inactivation of MAPK activity | 2 | 0.045176392 | DUSP2, DUSP8 |
| Biological Process | brain development | 3 | 0.047788991 | EPHA7, EGR2, DPYSL2 |
| Biological Process | intrinsic apoptotic signaling pathway by p53 class mediator | 2 | 0.048703923 | E2F1, E2F2 |