A、B、C The expression of APP 、BACE1、IDE in the hippocampus of each group of mice. D, E, F The expression of APP, BACE1, DE in the cortex of each group of mice. a: the control group. b: the model group. c: the 2 periods of EA treatment group. d: the 3 periods of EA treatment group. G The level of APP, BACE1,IDE in the hippocampus was indicated by column chart of each group of mice. APP: ****p < 0.0001 versus the control group, ####p < 0.0001 versus the model group, ΔΔΔP < 0.001 versus the 2 periods of EA treatment group. BACE1: ****p < 0.0001 versus the control group, ##p < 0.01 and ###p < 0.001 versus the model group, ΔP < 0.05 versus the 2 periods of EA treatment group. IDE: ****p < 0.0001 versus the control group, ###p < 0.001 and ####P < 0.0001 versus the model group, ΔP < 0.05 versus the 2 periods of EA treatment group. H The level of APP 、BACE1、IDE in the cortex was indicated by column chart of each group of mice. APP: ***p < 0.001 versus the control group, #p < 0.05 and ##p < 0.01 versus the model group, ΔP < 0.05 versus the 2 periods of EA treatment group. BACE1: ***p < 0.001 versus the control group, #p < 0.05 versus the model group. IDE: ***p < 0.001 versus the control group, #p < 0.05 versus the model group, (n = 6 in each group).