TABLE 3.

Active fractions for all double mutants in a library compared to active fractions of the subset predicted by SwiftLib

Library no.	Diversified positions	SwiftLib codona		SwiftLib theoretical aa diversity	Overall active fraction	SwiftLib active fraction (no. of observations)b
		Position 1	Position 2
1	33, 40	VNC	NNS	252	0.94	0.97 (173)
2	40, 47	NNS	NDC	252	0.98	0.97 (68)
3	45, 87	RNS	NWC	96	0.82	1.00 (17)
4	32, 38	NNM	BRS	190	0.96	0.92 (38)
5	33, 45	NNS	RBG	126	1.00	1.00 (48)
6	47, 91	NNM	GTA	19	1.00	NA (0)
7	34, 35	AVC	GCA	3	0.90	NA (0)
8	74, 83	GCA	AAC	1	0.21	NA (0)

^aN = G, T, A, or C; V = G, T, or A; B = G, T, or C; M = A or C; R = A or G; W = A or T; S = G or C; K = G or T.

^bNA, not applicable.