Skip to main content
. 2020 Jan 31;94(4):e01120-19. doi: 10.1128/JVI.01120-19

TABLE 5.

Details of the DH677.3, A32, and N12-i3 interfaces

Region BSA (Å2) fora :
DH677.3 fab-gp12093TH057 coree-M48U1 A32 Fab- ID293TH057 (4YC2) N12-i3 fab-gp12093TH057 coree+N/C-M48U1 (5W4L)
gp120 total 925 850 803
    7/8-stranded β-sheet 248 0 754
    Layer 1 542 645 49
    Layer 2 135 205 0
    Layer 3 0 0 0
Heavy chain total 475 614 711
    FWR 0 17 16
    CDR H1 16 103 39
    CDR H2 84 83 440
    CDR H3 375 411 216
Light chain total 498 234 142
    FWR 95 0 0
    CDR L1 238 126 10
    CDR L2 27 0 0
    CDR L3 138 108 132
Heavy- and light-chain total 973 848 853
a

Details are based on the DH677.3-gp12093TH057coree -M48U1, A32 Fab-ID293TH057, and N12-i3 Fab-gp12093TH057coree+N/C-M48U1 structures, as calculated by the EBI PISA server (http://www.ebi.ac.uk/msd-srv/prot_int/cgi-bin/piserver). The two copies in the asymmetric unit of the DH677.3, A32, and N12-i3 complexes are averaged.