FIG 6.
IDV infection induced two-phase inflammation in mice. NF-κB-luciferase mice were infected with 105 TCID50 of D/5920 intranasally. (A) Bioluminescence was measured from 1 to 7 dpi by inoculation of luciferin intranasally (0.75 mg kg−1) and using the IVIS system. The scale on the right indicates the average radiance, calculated as the sum of the photons per second from each pixel inside the region of interest (ROI)/number of pixels (photons/s/cm2/sr). (B) Bioluminescence activity was quantified using the Living Image software and represented as a graph. fc, fold change; ctrl, control.