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Effects of TKII-12 on vascular endothelial growth factor (VEGF)-induced HRMECs tube formation on Matrigel. The left panel is the representative phase-contrast micrographs of HRMECs exposed to different culture medium at 6 h (magnification 20×). The right panel presents the quantitative graph of the relative percentage of tube length. Each value represents the mean ± SEM of triplicate measurements. **p < 0.01 versus the VEGF group. ##p < 0.01 versus the control group.
