Table 5.

Fold change¹ (over SO-S group) measured for the indicated metabolites in H, Tiv, Tor, SO-Tiv and SO-Tor group.

Metabolite	H	Tiv	Tor	SO-Tiv	SO-Tor
L-Arginine	1.1 ± 0.1n.s	0.8 ± 0.1*	0.7 ± 0.1**	1.9 ± 0.2***	1.8 ± 0.1***
L-Citrulline	1.3 ± 0.1*	2.8 ± 0.1***	3.2 ± 0.3***	0.9 ± 0.2n.s	0.7 ± 0.2*
L-Ornithine	1.1 ± 0.3n.s.	1.0 ± 0.1n.s.	1.0 ± 0.2n.s.	1.1 ± 0.2n.s.	1.0 ± 0.1n.s.

Metabolites were extracted from rat brains and analyzed by Mass Spectrometry (see “Materials and Methods” section). ¹(n = 3. Shown is mean ± SEM) ***p < 0.001; **p < 0.01; *p < 0.05; n.s.: non statistically different from SO-S group.