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. 2020 Jan 25;17:100606. doi: 10.1016/j.ajoc.2020.100606

Table 1.

Systemic manifestations of cobalt toxicity.

Organ System Clinical Manifestations
Cardiovascular System Cardiomyopathy
Electrocardiographic changes
Hypertension
Tachycardia
Peripheral and Central Nervous System Sensorineural hearing loss
Tinnitus
Vertigo
Poor concentration
Memory loss
Disorientation
Depression
Irritability
Fatigue
Anxiety
Tremor
Incoordination
Headaches
Muscle weakness
Peripheral neuropathy
Gait disturbance
Endocrine System Hypothyroidism
Chronic Thyroiditis
Hematological System
Polycythemia
Respiratory System Asthma
Hypersensitivity pneumonitis
Interstitial pneumonia
Dermatological System Contact dermatitis
Acne
Skin rashes