Supplemental Figure 2.

A and B: Mean arterial blood pressure (MAP; A) and response to KCl (30 mmol/L; B) in thoracic aortic segments in both wild-type (WT) and Marfan syndrome (MFS) mice with or without SIL treatment. A and B: Gray shading indicates mice treated with sildenafil. B: Values are expressed as a percentage of WT mice. Data are expressed as means ± SEM (A and B). n = 5 to 6 per group (B). ^†P < 0.05 versus untreated MFS mice (two-way analysis of variance with Sidak's post-hoc test).