Table 6.
Parameters and values utilized in sensitivity analyses.
| Scenario | Parameter | Base value | Sensitivity value | Source |
|---|---|---|---|---|
| Full vaccine price | Vaccine price per dose | $0.20 | $4.60 | [17] |
| Low treatment seeking | Treatment seeking proportion | [34] | ||
| Local | 1.74% | 0.87% | ||
| Regional | 7.35% | 3.675% | ||
| Distant | 17.46% | 8.73% | ||
| High treatment seeking | Treatment seeking proportion | [34] | ||
| Local | 1.74% | 3.48% | ||
| Regional | 7.35% | 14.7% | ||
| Distant | 17.46% | 34.92% | ||
| Low health system costs | Incremental health system cost (routine) | $4.59 | $1.73 | [38], [46] |
| High health system costs | Incremental health system cost (routine) | $4.59 | $6.32 | [38], [46] |
| Low vaccine coverage | Coverage in year of introduction | Assumption based on expert consultation | ||
| Dose 1 | 70% | 55% | ||
| Dose 2 | 65% | 50% | ||
| Coverage in first year campaign | ||||
| Dose 1 | 80% | 55% | ||
| Dose 2 | 75% | 50% | ||
| High vaccine coverage | Coverage in year of introduction | |||
| Dose 1 | 70% | 95% | ||
| Dose 2 | 65% | 90% | ||
| Coverage in first year campaign | ||||
| Dose 1 | 80% | 95% | ||
| Dose 2 | 75% | 90% | ||
| Low healthcare costs | Household cost per treated woman | Cost calculations see Annex 1 | ||
| Local cancer | $4,816.18 | $3,315.71 | ||
| Regional cancer | $5,715.62 | $4,215.15 | ||
| Distant cancer | $5,132.13 | $5,132.13 | ||
| High healthcare costs | Household cost per treated woman | Cost calculations see Annex 1 | ||
| Local cancer | $4,816.18 | $6,273.11 | ||
| Regional cancer | $5,715.62 | $8,060.68 | ||
| Distant cancer | $5,132.13 | $6,616.32 | ||
| 1 dose = 2 dose efficacy | Efficacy after primary dose 1 | 32.5% | 65% | [27], [28] |
| Cross protection | Efficacy after primary dose 2 | 65% | 80% | [32] |