Fig. 5.

Overlays of tumour contours from MRI/MSOT image pairs before and after landmark-based optimization. (a) Comparison of a tumour outline before and after landmark-based tumour registration. (b) Quantification of the improvement in Dice similarity coefficient ($n=15$ tumours, combined data for conventional and novel MRI holder geometry). ** $p<0.01$ by paired two-tailed $t$-test (equal variances).